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Low and High Molecular Weight FGF-2 Have Differential Effects on Astrocyte Proliferation, but Are Both Protective Against Aβ-Induced Cytotoxicity

Astrocytes are the most abundant type of glial cells in the brain, and they play a key role in Alzheimer’s disease (AD). Fibroblast Growth Factor-2 (FGF-2) has been implicated as a potential therapeutic agent for treating AD. In the present study, we investigated the protective effects of low molecu...

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Detalles Bibliográficos
Autores principales: Chen, Xi, Li, Zhaojin, Cheng, Yong, Kardami, Elissavet, Loh, Y. Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992557/
https://www.ncbi.nlm.nih.gov/pubmed/32038161
http://dx.doi.org/10.3389/fnmol.2019.00328