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Inflammatory Dendritic Cells, Regulated by IL-4 Receptor Alpha Signaling, Control Replication, and Dissemination of Leishmania major in Mice

Leishmaniasis is a vector-borne disease caused by Leishmania parasites. Macrophages are considered the primary parasite host cell, but dendritic cells (DCs) play a critical role in initiating adaptive immunity and controlling Leishmania infection. Accordingly, our previous study in CD11c(cre)IL-4Rα(...

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Detalles Bibliográficos
Autores principales: Hurdayal, Ramona, Nieuwenhuizen, Natalie Eva, Khutlang, Rethabile, Brombacher, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992597/
https://www.ncbi.nlm.nih.gov/pubmed/32039054
http://dx.doi.org/10.3389/fcimb.2019.00479