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Evaluation of the antiviral activity of orlistat (tetrahydrolipstatin) against dengue virus, Japanese encephalitis virus, Zika virus and chikungunya virus

Many mosquito transmitted viruses of the genera Alphavirus and Flavivirus are human pathogens of significant concern, and there is currently no specific antiviral for any member of these two genera. This study sought to investigate the broad utility of orlistat (tetrahydrolipstatin) in reducing viru...

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Detalles Bibliográficos
Autores principales: Hitakarun, Atitaya, Khongwichit, Sarawut, Wikan, Nitwara, Roytrakul, Sittiruk, Yoksan, Sutee, Rajakam, Supoth, Davidson, Andrew D., Smith, Duncan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992670/
https://www.ncbi.nlm.nih.gov/pubmed/32001767
http://dx.doi.org/10.1038/s41598-020-58468-8