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A RAF-SnRK2 kinase cascade mediates early osmotic stress signaling in higher plants
Osmoregulation is important for plant growth, development and response to environmental changes. SNF1-related protein kinase 2s (SnRK2s) are quickly activated by osmotic stress and are central components in osmotic stress and abscisic acid (ABA) signaling pathways; however, the upstream components r...
| Autores principales: | , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992735/ https://www.ncbi.nlm.nih.gov/pubmed/32001690 http://dx.doi.org/10.1038/s41467-020-14477-9 |
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| author | Lin, Zhen Li, Yuan Zhang, Zhengjing Liu, Xiaolei Hsu, Chuan-Chih Du, Yanyan Sang, Tian Zhu, Chen Wang, Yubei Satheesh, Viswanathan Pratibha, Pritu Zhao, Yang Song, Chun-Peng Tao, W. Andy Zhu, Jian-Kang Wang, Pengcheng |
| author_facet | Lin, Zhen Li, Yuan Zhang, Zhengjing Liu, Xiaolei Hsu, Chuan-Chih Du, Yanyan Sang, Tian Zhu, Chen Wang, Yubei Satheesh, Viswanathan Pratibha, Pritu Zhao, Yang Song, Chun-Peng Tao, W. Andy Zhu, Jian-Kang Wang, Pengcheng |
| author_sort | Lin, Zhen |
| collection | PubMed |
| description | Osmoregulation is important for plant growth, development and response to environmental changes. SNF1-related protein kinase 2s (SnRK2s) are quickly activated by osmotic stress and are central components in osmotic stress and abscisic acid (ABA) signaling pathways; however, the upstream components required for SnRK2 activation and early osmotic stress signaling are still unknown. Here, we report a critical role for B2, B3 and B4 subfamilies of Raf-like kinases (RAFs) in early osmotic stress as well as ABA signaling in Arabidopsis thaliana. B2, B3 and B4 RAFs are quickly activated by osmotic stress and are required for phosphorylation and activation of SnRK2s. Analyses of high-order mutants of RAFs reveal critical roles of the RAFs in osmotic stress tolerance and ABA responses as well as in growth and development. Our findings uncover a kinase cascade mediating osmoregulation in higher plants. |
| format | Online Article Text |
| id | pubmed-6992735 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2020 |
| publisher | Nature Publishing Group UK |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-69927352020-02-03 A RAF-SnRK2 kinase cascade mediates early osmotic stress signaling in higher plants Lin, Zhen Li, Yuan Zhang, Zhengjing Liu, Xiaolei Hsu, Chuan-Chih Du, Yanyan Sang, Tian Zhu, Chen Wang, Yubei Satheesh, Viswanathan Pratibha, Pritu Zhao, Yang Song, Chun-Peng Tao, W. Andy Zhu, Jian-Kang Wang, Pengcheng Nat Commun Article Osmoregulation is important for plant growth, development and response to environmental changes. SNF1-related protein kinase 2s (SnRK2s) are quickly activated by osmotic stress and are central components in osmotic stress and abscisic acid (ABA) signaling pathways; however, the upstream components required for SnRK2 activation and early osmotic stress signaling are still unknown. Here, we report a critical role for B2, B3 and B4 subfamilies of Raf-like kinases (RAFs) in early osmotic stress as well as ABA signaling in Arabidopsis thaliana. B2, B3 and B4 RAFs are quickly activated by osmotic stress and are required for phosphorylation and activation of SnRK2s. Analyses of high-order mutants of RAFs reveal critical roles of the RAFs in osmotic stress tolerance and ABA responses as well as in growth and development. Our findings uncover a kinase cascade mediating osmoregulation in higher plants. Nature Publishing Group UK 2020-01-30 /pmc/articles/PMC6992735/ /pubmed/32001690 http://dx.doi.org/10.1038/s41467-020-14477-9 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
| spellingShingle | Article Lin, Zhen Li, Yuan Zhang, Zhengjing Liu, Xiaolei Hsu, Chuan-Chih Du, Yanyan Sang, Tian Zhu, Chen Wang, Yubei Satheesh, Viswanathan Pratibha, Pritu Zhao, Yang Song, Chun-Peng Tao, W. Andy Zhu, Jian-Kang Wang, Pengcheng A RAF-SnRK2 kinase cascade mediates early osmotic stress signaling in higher plants |
| title | A RAF-SnRK2 kinase cascade mediates early osmotic stress signaling in higher plants |
| title_full | A RAF-SnRK2 kinase cascade mediates early osmotic stress signaling in higher plants |
| title_fullStr | A RAF-SnRK2 kinase cascade mediates early osmotic stress signaling in higher plants |
| title_full_unstemmed | A RAF-SnRK2 kinase cascade mediates early osmotic stress signaling in higher plants |
| title_short | A RAF-SnRK2 kinase cascade mediates early osmotic stress signaling in higher plants |
| title_sort | raf-snrk2 kinase cascade mediates early osmotic stress signaling in higher plants |
| topic | Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992735/ https://www.ncbi.nlm.nih.gov/pubmed/32001690 http://dx.doi.org/10.1038/s41467-020-14477-9 |
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