Inhibition of AIM2 inflammasome activation alleviates GSDMD-induced pyroptosis in early brain injury after subarachnoid haemorrhage

Only a few types of inflammasomes have been described in central nervous system cells. Among these, the absent in melanoma 2 (AIM2) inflammasome is primarily found in neurons, is highly specific and can be activated only by double-stranded DNA. Although it has been demonstrated that the AIM2 inflamm...

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Detalles Bibliográficos
Autores principales: Yuan, Bin, Zhou, Xiao-ming, You, Zong-qi, Xu, Wei-dong, Fan, Jie-mei, Chen, Shu-juan, Han, Yan-ling, Wu, Qi, Zhang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992766/
https://www.ncbi.nlm.nih.gov/pubmed/32001670
http://dx.doi.org/10.1038/s41419-020-2248-z

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