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Identification of the leptin receptor sequences crucial for the STAT3-Independent control of metabolism
BACKGROUND: Leptin acts via its receptor, LepRb, on specialized neurons in the brain to modulate energy balance and glucose homeostasis. LepRb→STAT3 signaling plays a crucial role in leptin action, but LepRb also mediates an additional as-yet-unidentified signal (Signal 2) that is important for lept...
Autores principales: | Barnes, Tammy M., Shah, Kimi, Allison, Margaret B., Steinl, Gabrielle K., Gordian, Desiree, Sabatini, Paul V., Tomlinson, Abigail J., Cheng, Wenwen, Jones, Justin C., Zhu, Qing, Faber, Chelsea, Myers, Martin G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992902/ https://www.ncbi.nlm.nih.gov/pubmed/32029227 http://dx.doi.org/10.1016/j.molmet.2019.12.013 |
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