Near infrared photoimmunotherapy targeting DLL3 for small cell lung cancer

BACKGROUND: Small cell lung cancer (SCLC) has a poor prognosis, and its treatment options are limited. Delta-like protein 3 (DLL3) is expressed specifically in SCLC and is considered a promising therapeutic target for patients with this disease. Rovalpituzumab tesirine (Rova-T) was the first antibod...

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Detalles Bibliográficos
Autores principales: Isobe, Yoshitaka, Sato, Kazuhide, Nishinaga, Yuko, Takahashi, Kazuomi, Taki, Shunichi, Yasui, Hirotoshi, Shimizu, Misae, Endo, Rena, Koike, Chiaki, Kuramoto, Noriko, Yukawa, Hiroshi, Nakamura, Shota, Fukui, Takayuki, Kawaguchi, Koji, Chen-Yoshikawa, Toyofumi F., Baba, Yoshinobu, Hasegawa, Yoshinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992936/
https://www.ncbi.nlm.nih.gov/pubmed/31981983
http://dx.doi.org/10.1016/j.ebiom.2020.102632

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