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Interleukin-2-Inducible T-Cell Kinase Deficiency Impairs Early Pulmonary Protection Against Mycobacterium tuberculosis Infection

Interleukin-2 (IL-2) inducible T-cell kinase (ITK) is a non-receptor tyrosine kinase highly expressed in T-cell lineages and regulates multiple aspects of T-cell development and function, mainly through its function downstream of the T-cell receptor. Itk deficiency can lead to CD4 lymphopenia and Ep...

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Detalles Bibliográficos
Autores principales:	Huang, Lu, Ye, Kaixiong, McGee, Michael C., Nidetz, Natalie F., Elmore, Jessica P., Limper, Candice B., Southard, Teresa L., Russell, David G., August, Avery, Huang, Weishan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993117/ https://www.ncbi.nlm.nih.gov/pubmed/32038633 http://dx.doi.org/10.3389/fimmu.2019.03103

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