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Arthroscopic Harvesting of Autologous Bone Graft for Use as a Mesenchymal Stem Cell Carrier in Anterior Cruciate Ligament Reconstruction
Anterior cruciate ligament (ACL) tears are detrimental to knee stability and normal function. Although the standard of treatment is an ACL reconstruction, technical improvements are sought to enhance clinical outcomes due to the appreciable failure rate. The use of autologous biologic substances as...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993187/ https://www.ncbi.nlm.nih.gov/pubmed/32021773 http://dx.doi.org/10.1016/j.eats.2019.08.018 |
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author | van Gogh, Angelica Marie Li, Xingguang Youn, Gun Min Alvarez, Alyssa Yin, Sophia Chakrabarti, Moyukh O. McGahan, Patrick J. Chen, James L. |
author_facet | van Gogh, Angelica Marie Li, Xingguang Youn, Gun Min Alvarez, Alyssa Yin, Sophia Chakrabarti, Moyukh O. McGahan, Patrick J. Chen, James L. |
author_sort | van Gogh, Angelica Marie |
collection | PubMed |
description | Anterior cruciate ligament (ACL) tears are detrimental to knee stability and normal function. Although the standard of treatment is an ACL reconstruction, technical improvements are sought to enhance clinical outcomes due to the appreciable failure rate. The use of autologous biologic substances as carriers of stem cells are desirable because of their multipotent properties. Traditionally, the collection of autologous bone grafts is through an open incision of the iliac crest, which causes substantial morbidity to the patient. This Technical Note describes an arthroscopic, minimally invasive collection method of autologous tibial and femoral bone graft to use in backfilling the tunnels during an ACL reconstruction to improve graft incorporation and clinical outcomes. |
format | Online Article Text |
id | pubmed-6993187 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-69931872020-02-04 Arthroscopic Harvesting of Autologous Bone Graft for Use as a Mesenchymal Stem Cell Carrier in Anterior Cruciate Ligament Reconstruction van Gogh, Angelica Marie Li, Xingguang Youn, Gun Min Alvarez, Alyssa Yin, Sophia Chakrabarti, Moyukh O. McGahan, Patrick J. Chen, James L. Arthrosc Tech Technical Note Anterior cruciate ligament (ACL) tears are detrimental to knee stability and normal function. Although the standard of treatment is an ACL reconstruction, technical improvements are sought to enhance clinical outcomes due to the appreciable failure rate. The use of autologous biologic substances as carriers of stem cells are desirable because of their multipotent properties. Traditionally, the collection of autologous bone grafts is through an open incision of the iliac crest, which causes substantial morbidity to the patient. This Technical Note describes an arthroscopic, minimally invasive collection method of autologous tibial and femoral bone graft to use in backfilling the tunnels during an ACL reconstruction to improve graft incorporation and clinical outcomes. Elsevier 2019-12-18 /pmc/articles/PMC6993187/ /pubmed/32021773 http://dx.doi.org/10.1016/j.eats.2019.08.018 Text en © 2019 by the Arthroscopy Association of North America. Published by Elsevier. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Technical Note van Gogh, Angelica Marie Li, Xingguang Youn, Gun Min Alvarez, Alyssa Yin, Sophia Chakrabarti, Moyukh O. McGahan, Patrick J. Chen, James L. Arthroscopic Harvesting of Autologous Bone Graft for Use as a Mesenchymal Stem Cell Carrier in Anterior Cruciate Ligament Reconstruction |
title | Arthroscopic Harvesting of Autologous Bone Graft for Use as a Mesenchymal Stem Cell Carrier in Anterior Cruciate Ligament Reconstruction |
title_full | Arthroscopic Harvesting of Autologous Bone Graft for Use as a Mesenchymal Stem Cell Carrier in Anterior Cruciate Ligament Reconstruction |
title_fullStr | Arthroscopic Harvesting of Autologous Bone Graft for Use as a Mesenchymal Stem Cell Carrier in Anterior Cruciate Ligament Reconstruction |
title_full_unstemmed | Arthroscopic Harvesting of Autologous Bone Graft for Use as a Mesenchymal Stem Cell Carrier in Anterior Cruciate Ligament Reconstruction |
title_short | Arthroscopic Harvesting of Autologous Bone Graft for Use as a Mesenchymal Stem Cell Carrier in Anterior Cruciate Ligament Reconstruction |
title_sort | arthroscopic harvesting of autologous bone graft for use as a mesenchymal stem cell carrier in anterior cruciate ligament reconstruction |
topic | Technical Note |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993187/ https://www.ncbi.nlm.nih.gov/pubmed/32021773 http://dx.doi.org/10.1016/j.eats.2019.08.018 |
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