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Arthroscopic Harvesting of Autologous Bone Graft for Use as a Mesenchymal Stem Cell Carrier in Anterior Cruciate Ligament Reconstruction

Anterior cruciate ligament (ACL) tears are detrimental to knee stability and normal function. Although the standard of treatment is an ACL reconstruction, technical improvements are sought to enhance clinical outcomes due to the appreciable failure rate. The use of autologous biologic substances as...

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Autores principales: van Gogh, Angelica Marie, Li, Xingguang, Youn, Gun Min, Alvarez, Alyssa, Yin, Sophia, Chakrabarti, Moyukh O., McGahan, Patrick J., Chen, James L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993187/
https://www.ncbi.nlm.nih.gov/pubmed/32021773
http://dx.doi.org/10.1016/j.eats.2019.08.018
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author van Gogh, Angelica Marie
Li, Xingguang
Youn, Gun Min
Alvarez, Alyssa
Yin, Sophia
Chakrabarti, Moyukh O.
McGahan, Patrick J.
Chen, James L.
author_facet van Gogh, Angelica Marie
Li, Xingguang
Youn, Gun Min
Alvarez, Alyssa
Yin, Sophia
Chakrabarti, Moyukh O.
McGahan, Patrick J.
Chen, James L.
author_sort van Gogh, Angelica Marie
collection PubMed
description Anterior cruciate ligament (ACL) tears are detrimental to knee stability and normal function. Although the standard of treatment is an ACL reconstruction, technical improvements are sought to enhance clinical outcomes due to the appreciable failure rate. The use of autologous biologic substances as carriers of stem cells are desirable because of their multipotent properties. Traditionally, the collection of autologous bone grafts is through an open incision of the iliac crest, which causes substantial morbidity to the patient. This Technical Note describes an arthroscopic, minimally invasive collection method of autologous tibial and femoral bone graft to use in backfilling the tunnels during an ACL reconstruction to improve graft incorporation and clinical outcomes.
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spelling pubmed-69931872020-02-04 Arthroscopic Harvesting of Autologous Bone Graft for Use as a Mesenchymal Stem Cell Carrier in Anterior Cruciate Ligament Reconstruction van Gogh, Angelica Marie Li, Xingguang Youn, Gun Min Alvarez, Alyssa Yin, Sophia Chakrabarti, Moyukh O. McGahan, Patrick J. Chen, James L. Arthrosc Tech Technical Note Anterior cruciate ligament (ACL) tears are detrimental to knee stability and normal function. Although the standard of treatment is an ACL reconstruction, technical improvements are sought to enhance clinical outcomes due to the appreciable failure rate. The use of autologous biologic substances as carriers of stem cells are desirable because of their multipotent properties. Traditionally, the collection of autologous bone grafts is through an open incision of the iliac crest, which causes substantial morbidity to the patient. This Technical Note describes an arthroscopic, minimally invasive collection method of autologous tibial and femoral bone graft to use in backfilling the tunnels during an ACL reconstruction to improve graft incorporation and clinical outcomes. Elsevier 2019-12-18 /pmc/articles/PMC6993187/ /pubmed/32021773 http://dx.doi.org/10.1016/j.eats.2019.08.018 Text en © 2019 by the Arthroscopy Association of North America. Published by Elsevier. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Technical Note
van Gogh, Angelica Marie
Li, Xingguang
Youn, Gun Min
Alvarez, Alyssa
Yin, Sophia
Chakrabarti, Moyukh O.
McGahan, Patrick J.
Chen, James L.
Arthroscopic Harvesting of Autologous Bone Graft for Use as a Mesenchymal Stem Cell Carrier in Anterior Cruciate Ligament Reconstruction
title Arthroscopic Harvesting of Autologous Bone Graft for Use as a Mesenchymal Stem Cell Carrier in Anterior Cruciate Ligament Reconstruction
title_full Arthroscopic Harvesting of Autologous Bone Graft for Use as a Mesenchymal Stem Cell Carrier in Anterior Cruciate Ligament Reconstruction
title_fullStr Arthroscopic Harvesting of Autologous Bone Graft for Use as a Mesenchymal Stem Cell Carrier in Anterior Cruciate Ligament Reconstruction
title_full_unstemmed Arthroscopic Harvesting of Autologous Bone Graft for Use as a Mesenchymal Stem Cell Carrier in Anterior Cruciate Ligament Reconstruction
title_short Arthroscopic Harvesting of Autologous Bone Graft for Use as a Mesenchymal Stem Cell Carrier in Anterior Cruciate Ligament Reconstruction
title_sort arthroscopic harvesting of autologous bone graft for use as a mesenchymal stem cell carrier in anterior cruciate ligament reconstruction
topic Technical Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993187/
https://www.ncbi.nlm.nih.gov/pubmed/32021773
http://dx.doi.org/10.1016/j.eats.2019.08.018
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