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Aligned chitosan nanofiber hydrogel grafted with peptides mimicking bioactive brain-derived neurotrophic factor and vascular endothelial growth factor repair long-distance sciatic nerve defects in rats
Autologous nerve transplantation, which is the gold standard for clinical treatment of peripheral nerve injury, still has many limitations. In this study, aligned chitosan fiber hydrogel (ACG) grafted with a bioactive peptide mixture consisting of RGI (Ac-RGIDKRHWNSQGG) and KLT (Ac-KLTWQELYQLKYKGIGG...
Autores principales: | Rao, Feng, Wang, Yanhua, Zhang, Dianying, Lu, Changfeng, Cao, Zheng, Sui, Jiajie, Wu, Mengjiao, Zhang, Yawen, Pi, Wei, Wang, Bo, Kou, Yuhui, Wang, Xiumei, Zhang, Peixun, Jiang, Baoguo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993237/ https://www.ncbi.nlm.nih.gov/pubmed/32042324 http://dx.doi.org/10.7150/thno.36272 |
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