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Aligned chitosan nanofiber hydrogel grafted with peptides mimicking bioactive brain-derived neurotrophic factor and vascular endothelial growth factor repair long-distance sciatic nerve defects in rats

Autologous nerve transplantation, which is the gold standard for clinical treatment of peripheral nerve injury, still has many limitations. In this study, aligned chitosan fiber hydrogel (ACG) grafted with a bioactive peptide mixture consisting of RGI (Ac-RGIDKRHWNSQGG) and KLT (Ac-KLTWQELYQLKYKGIGG...

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Detalles Bibliográficos
Autores principales: Rao, Feng, Wang, Yanhua, Zhang, Dianying, Lu, Changfeng, Cao, Zheng, Sui, Jiajie, Wu, Mengjiao, Zhang, Yawen, Pi, Wei, Wang, Bo, Kou, Yuhui, Wang, Xiumei, Zhang, Peixun, Jiang, Baoguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993237/
https://www.ncbi.nlm.nih.gov/pubmed/32042324
http://dx.doi.org/10.7150/thno.36272

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