Generation and characterization of a mitotane-resistant adrenocortical cell line

Mitotane is the only drug approved for the therapy of adrenocortical carcinoma (ACC). Its clinical use is limited by the occurrence of relapse during therapy. To investigate the underlying mechanisms in vitro, we here generated mitotane-resistant cell lines. After long-term pulsed treatment of HAC-1...

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Detalles Bibliográficos
Autores principales: Seidel, Eric, Walenda, Gudrun, Messerschmidt, Clemens, Obermayer, Benedikt, Peitzsch, Mirko, Wallace, Paal, Bahethi, Rohini, Yoo, Taekyeong, Choi, Murim, Schrade, Petra, Bachmann, Sebastian, Liebisch, Gerhard, Eisenhofer, Graeme, Beule, Dieter, Scholl, Ute I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993260/
https://www.ncbi.nlm.nih.gov/pubmed/31910152
http://dx.doi.org/10.1530/EC-19-0510

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