ALKBH5-mediated m(6)A demethylation of lncRNA PVT1 plays an oncogenic role in osteosarcoma

BACKGROUND: Osteosarcoma (OS) is one of the most common malignant bone tumors. Plasmacytoma variant translocation 1 (PVT1) is a well-known oncogenic long noncoding RNA (lncRNA). However, to date, the regulatory mechanism of PVT1 upregulation in OS remains unknown. METHODS: qRT-PCR was carried out to...

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Detalles Bibliográficos
Autores principales: Chen, Shuo, Zhou, Liwu, Wang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993345/
https://www.ncbi.nlm.nih.gov/pubmed/32021563
http://dx.doi.org/10.1186/s12935-020-1105-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993345/
https://www.ncbi.nlm.nih.gov/pubmed/32021563
http://dx.doi.org/10.1186/s12935-020-1105-6

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