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ALKBH5-mediated m(6)A demethylation of lncRNA PVT1 plays an oncogenic role in osteosarcoma

BACKGROUND: Osteosarcoma (OS) is one of the most common malignant bone tumors. Plasmacytoma variant translocation 1 (PVT1) is a well-known oncogenic long noncoding RNA (lncRNA). However, to date, the regulatory mechanism of PVT1 upregulation in OS remains unknown. METHODS: qRT-PCR was carried out to...

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Detalles Bibliográficos
Autores principales:	Chen, Shuo, Zhou, Liwu, Wang, Yang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993345/ https://www.ncbi.nlm.nih.gov/pubmed/32021563 http://dx.doi.org/10.1186/s12935-020-1105-6

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