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Safety, tolerability and immunogenicity of V934/V935 hTERT vaccination in cancer patients with selected solid tumors: a phase I study

BACKGROUND: Human telomerase reverse transcriptase (hTERT) is an antigen that may represent a target for a novel anti-cancer strategy. A pilot, phase I study tested the safety and feasibility of a prime-boost immunization regimen based on V935, an adenoviral type 6 vector vaccine expressing a modifi...

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Detalles Bibliográficos
Autores principales:	Aurisicchio, Luigi, Fridman, Arthur, Mauro, David, Sheloditna, Rose, Chiappori, Alberto, Bagchi, Ansuman, Ciliberto, Gennaro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993365/ https://www.ncbi.nlm.nih.gov/pubmed/32000810 http://dx.doi.org/10.1186/s12967-020-02228-9

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