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Detection of suspicious interactions of spiking covariates in methylation data
BACKGROUND: In methylation analyses like epigenome-wide association studies, a high amount of biomarkers is tested for an association between the measured continuous outcome and different covariates. In the case of a continuous covariate like smoking pack years (SPY), a measure of lifetime exposure...
Autores principales: | Sieg, Miriam, Richter, Gesa, Schaefer, Arne S., Kruppa, Jochen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993406/ https://www.ncbi.nlm.nih.gov/pubmed/32000657 http://dx.doi.org/10.1186/s12859-020-3364-6 |
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