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Detection of suspicious interactions of spiking covariates in methylation data

BACKGROUND: In methylation analyses like epigenome-wide association studies, a high amount of biomarkers is tested for an association between the measured continuous outcome and different covariates. In the case of a continuous covariate like smoking pack years (SPY), a measure of lifetime exposure...

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Detalles Bibliográficos
Autores principales: Sieg, Miriam, Richter, Gesa, Schaefer, Arne S., Kruppa, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993406/
https://www.ncbi.nlm.nih.gov/pubmed/32000657
http://dx.doi.org/10.1186/s12859-020-3364-6

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