Decreased expression of Rev-Erbα in the epileptic foci of temporal lobe epilepsy and activation of Rev-Erbα have anti-inflammatory and neuroprotective effects in the pilocarpine model

BACKGROUND: A hallmark of temporal lobe epilepsy (TLE) is brain inflammation accompanied by neuronal demise. Accumulating evidence demonstrates that Rev-Erbα is involved in regulating neuroinflammation and determining the fate of neurons. Therefore, we studied the expression and cellular distributio...

Descripción completa

Detalles Bibliográficos
Autores principales: Yue, Jiong, He, Jiaojiang, Wei, Yujia, Shen, Kaifeng, Wu, Kefu, Yang, Xiaolin, Liu, Shiyong, Zhang, Chunqing, Yang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993411/
https://www.ncbi.nlm.nih.gov/pubmed/32005256
http://dx.doi.org/10.1186/s12974-020-1718-7

Ejemplares similares

Ejemplares similares