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Contribution of Pyk2 pathway and reactive oxygen species (ROS) to the anti-cancer effects of eicosapentaenoic acid (EPA) in PC3 prostate cancer cells
BACKGROUND: n-3 polyunsaturated fatty acids (n-3 PUFAs), including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), are thought to exert protective effects in cardiovascular diseases. In addition, n-3 PUFAs have demonstrated anti-cancer effects in vitro and in vivo. OBJECTIVE: We investig...
Autores principales: | Oono, Keiichi, Ohtake, Kazuo, Watanabe, Chie, Shiba, Sachiko, Sekiya, Takashi, Kasono, Keizo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993438/ https://www.ncbi.nlm.nih.gov/pubmed/32005121 http://dx.doi.org/10.1186/s12944-019-1122-4 |
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