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Polygenic risk for coronary heart disease acts through atherosclerosis in type 2 diabetes

BACKGROUND: Type 2 diabetes increases the risk of coronary heart disease (CHD), yet the mechanisms involved remain poorly described. Polygenic risk scores (PRS) provide an opportunity to understand risk factors since they reflect etiologic pathways from the entire genome. We therefore tested whether...

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Detalles Bibliográficos
Autores principales:	Lu, Tianyuan, Forgetta, Vincenzo, Yu, Oriana H. Y., Mokry, Lauren, Gregory, Madeline, Thanassoulis, George, Greenwood, Celia M. T., Richards, J. Brent
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993460/ https://www.ncbi.nlm.nih.gov/pubmed/32000781 http://dx.doi.org/10.1186/s12933-020-0988-9

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