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Substance P participates in periodontitis by upregulating HIF-1α and RANKL/OPG ratio
BACKGROUND: Both substance P and hypoxia-inducible factor 1 alpha (HIF-1α) are involved in inflammation and angiogenesis. However, the relationship between substance P and HIF-1α in rat periodontitis is still unknown. METHODS: Ligation-induced rat periodontitis was established to observe the distrib...
Autores principales: | Yan, Kaixian, Lin, Qin, Tang, Kailiang, Liu, Shuang, Du, Yi, Yu, Xijiao, Li, Shu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993464/ https://www.ncbi.nlm.nih.gov/pubmed/32000757 http://dx.doi.org/10.1186/s12903-020-1017-9 |
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