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Cigarette and IL-17A synergistically induce bronchial epithelial-mesenchymal transition via activating IL-17R/NF-κB signaling

BACKGROUND: IL-17A directly induces epithelial-mesenchymal transition (EMT) in alveolar epithelial cells. It could coordinate with cigarette smoke extract (CSE) to promote proliferation of bronchial epithelial cells. In this study, we aim to explore the direct effect of IL-17A and CSE on EMT in bron...

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Detalles Bibliográficos
Autores principales:	Ma, Libing, Jiang, Ming, Zhao, Xiaoli, Sun, Jingyi, Pan, Qilu, Chu, Shuyuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993491/ https://www.ncbi.nlm.nih.gov/pubmed/32000730 http://dx.doi.org/10.1186/s12890-020-1057-6

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