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Dehydroepiandrosterone and Its CYP7B1 Metabolite 7α-Hydroxydehydroepiandrosterone Regulates 11β-Hydroxysteroid Dehydrogenase 1 Directions in Rat Leydig Cells

Background: The purpose of this study was to investigate cytochrome P450-7B1 (CYP7B1) in the human and rat testes to regulate 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) activity. We hypothesized that dehydroepiandrosterone (DHEA) and its product 7α-hydroxydehydroepiandrosterone (7αOHD) after cata...

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Detalles Bibliográficos
Autores principales:	Zhu, Qiqi, Dong, Yaoyao, Li, Xiaoheng, Ni, Chaobo, Huang, Tongliang, Sun, Jianliang, Ge, Ren-Shan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993528/ https://www.ncbi.nlm.nih.gov/pubmed/32038478 http://dx.doi.org/10.3389/fendo.2019.00886

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