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X-ray snapshots reveal conformational influence on active site ligation during metalloprotein folding
Cytochrome c (cyt c) has long been utilized as a model system to study metalloprotein folding dynamics and the interplay between active site ligation and tertiary structure. However, recent reports regarding the weakness of the native Fe(ii)–S bond (Fe–Met80) call into question the role of the activ...
Autores principales: | Hsu, Darren J., Leshchev, Denis, Rimmerman, Dolev, Hong, Jiyun, Kelley, Matthew S., Kosheleva, Irina, Zhang, Xiaoyi, Chen, Lin X. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993610/ https://www.ncbi.nlm.nih.gov/pubmed/32055348 http://dx.doi.org/10.1039/c9sc02630d |
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