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Efficient in vivo synthesis of lasso peptide pseudomycoidin proceeds in the absence of both the leader and the leader peptidase
Bacterial lasso peptides are made from linear ribosomally synthesized precursors by specific cleavage at the leader–core junction site of the precursor by a dedicated protease recognizing the leader, followed by cyclisation of the newly formed N-terminus of the core part with a side chain of the int...
Autores principales: | Zyubko, Tatyana, Serebryakova, Marina, Andreeva, Julia, Metelev, Mikhail, Lippens, Guy, Dubiley, Svetlana, Severinov, Konstantin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993621/ https://www.ncbi.nlm.nih.gov/pubmed/32055339 http://dx.doi.org/10.1039/c9sc02370d |
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