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Identifying cytochrome P450s involved in oxidative metabolism of synthetic cannabinoid N‐(adamantan‐1‐yl)‐1‐(5‐fluoropentyl)‐1H‐indole‐3‐carboxamide (STS‐135)
Synthetic cannabinoids (SCBs), designer drugs marketed as legal alternatives to marijuana, act as ligands to cannabinoid receptors; however, they have increased binding affinity and potency, resulting in toxicity symptoms such as cardiovascular incidents, seizures, and potentially death. N‐(adamanta...
Autores principales: | Jones, Sabrina, Yarbrough, Azure L., Fantegrossi, William E., Prather, Paul L., Bush, John M., Radominska‐Pandya, Anna, Fujiwara, Ryoichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993754/ https://www.ncbi.nlm.nih.gov/pubmed/32003945 http://dx.doi.org/10.1002/prp2.561 |
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