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Balthazar Score and Neutrophil-Lymphocytes Ratio in Acute Pancreatitis

Acute pancreatitis is a pathological entity that poses numerous diagnostic and treatment problems. Severe form is a real challenge for a physician because it has multiple obscure causes, as well as a complex pathophysiology. Thus, the diagnosis is difficult and the choice of the right time for surgi...

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Autores principales: PETRESCU, GS, GEORGESCU, I, PETRESCU, AM, RĂDULESCU, D, PETRESCU, MO, PĂTRAȘCU, Ș
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medical University Publishing House Craiova 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993759/
https://www.ncbi.nlm.nih.gov/pubmed/32042461
http://dx.doi.org/10.12865/CHSJ.45.03.11
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author PETRESCU, GS
GEORGESCU, I
PETRESCU, AM
RĂDULESCU, D
PETRESCU, MO
PĂTRAȘCU, Ș
author_facet PETRESCU, GS
GEORGESCU, I
PETRESCU, AM
RĂDULESCU, D
PETRESCU, MO
PĂTRAȘCU, Ș
author_sort PETRESCU, GS
collection PubMed
description Acute pancreatitis is a pathological entity that poses numerous diagnostic and treatment problems. Severe form is a real challenge for a physician because it has multiple obscure causes, as well as a complex pathophysiology. Thus, the diagnosis is difficult and the choice of the right time for surgical treatment is controversial, the treatment being more frequently nonspecific, supportive for the various affected systems and organs. On a group of 337 patients, laboratory and imaging investigations were performed to diagnose and determine the severity score of acute pancreatitis and the correlation level between the neutrophil-lymphocytes ratio values and the Balthazar score, as a valid assessment method for local and systemic inflammatory changes. The distribution’s study of acute pancreatitis by gender according to etiology confirms the predominance of the acute ethanolic pancreatitis in male, but also the higher proportion (54%) of male pancreatitis (181 man vs. 156 women) with gender ratio male/female 1.16/1. The neutrophil-lymphocytes ratio mean value varied according with the Balthazar severity score, that got higher as acute pancreatitis got more advanced and with a certain cut-off value can be considered a simple indicator to determine the severity of acute pancreatitis.
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spelling pubmed-69937592020-02-10 Balthazar Score and Neutrophil-Lymphocytes Ratio in Acute Pancreatitis PETRESCU, GS GEORGESCU, I PETRESCU, AM RĂDULESCU, D PETRESCU, MO PĂTRAȘCU, Ș Curr Health Sci J Original Paper Acute pancreatitis is a pathological entity that poses numerous diagnostic and treatment problems. Severe form is a real challenge for a physician because it has multiple obscure causes, as well as a complex pathophysiology. Thus, the diagnosis is difficult and the choice of the right time for surgical treatment is controversial, the treatment being more frequently nonspecific, supportive for the various affected systems and organs. On a group of 337 patients, laboratory and imaging investigations were performed to diagnose and determine the severity score of acute pancreatitis and the correlation level between the neutrophil-lymphocytes ratio values and the Balthazar score, as a valid assessment method for local and systemic inflammatory changes. The distribution’s study of acute pancreatitis by gender according to etiology confirms the predominance of the acute ethanolic pancreatitis in male, but also the higher proportion (54%) of male pancreatitis (181 man vs. 156 women) with gender ratio male/female 1.16/1. The neutrophil-lymphocytes ratio mean value varied according with the Balthazar severity score, that got higher as acute pancreatitis got more advanced and with a certain cut-off value can be considered a simple indicator to determine the severity of acute pancreatitis. Medical University Publishing House Craiova 2019 2019-09-30 /pmc/articles/PMC6993759/ /pubmed/32042461 http://dx.doi.org/10.12865/CHSJ.45.03.11 Text en Copyright © 2019, Medical University Publishing House Craiova http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an open-access article distributed under the terms of a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International Public License, which permits unrestricted use, adaptation, distribution and reproduction in any medium, non-commercially, provided the new creations are licensed under identical terms as the original work and the original work is properly cited.
spellingShingle Original Paper
PETRESCU, GS
GEORGESCU, I
PETRESCU, AM
RĂDULESCU, D
PETRESCU, MO
PĂTRAȘCU, Ș
Balthazar Score and Neutrophil-Lymphocytes Ratio in Acute Pancreatitis
title Balthazar Score and Neutrophil-Lymphocytes Ratio in Acute Pancreatitis
title_full Balthazar Score and Neutrophil-Lymphocytes Ratio in Acute Pancreatitis
title_fullStr Balthazar Score and Neutrophil-Lymphocytes Ratio in Acute Pancreatitis
title_full_unstemmed Balthazar Score and Neutrophil-Lymphocytes Ratio in Acute Pancreatitis
title_short Balthazar Score and Neutrophil-Lymphocytes Ratio in Acute Pancreatitis
title_sort balthazar score and neutrophil-lymphocytes ratio in acute pancreatitis
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993759/
https://www.ncbi.nlm.nih.gov/pubmed/32042461
http://dx.doi.org/10.12865/CHSJ.45.03.11
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