Cargando…
Nascent SecM chain interacts with outer ribosomal surface to stabilize translation arrest
SecM, a bacterial secretion monitor protein, posttranscriptionally regulates downstream gene expression via translation elongation arrest. SecM contains a characteristic amino acid sequence called the arrest sequence at its C-terminus, and this sequence acts within the ribosomal exit tunnel to stop...
Autores principales: | Muta, Mikihisa, Iizuka, Ryo, Niwa, Tatsuya, Guo, Yuanfang, Taguchi, Hideki, Funatsu, Takashi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993859/ https://www.ncbi.nlm.nih.gov/pubmed/31913464 http://dx.doi.org/10.1042/BCJ20190723 |
Ejemplares similares
-
Nascent SecM Chain Outside the Ribosome Reinforces Translation Arrest
por: Yang, Zhuohao, et al.
Publicado: (2015) -
Increased freedom of movement in the nascent chain results in dynamic changes in the structure of the SecM arrest motif
por: Bracken, Hazel A., et al.
Publicado: (2019) -
S-Adenosyl-l-methionine Induces Compaction of Nascent Peptide Chain inside the Ribosomal Exit Tunnel upon Translation Arrest in the Arabidopsis CGS1 Gene
por: Onoue, Noriyuki, et al.
Publicado: (2011) -
Mechanisms of ribosome stalling by SecM at multiple elongation steps
por: Zhang, Jun, et al.
Publicado: (2015) -
SecM-Stalled Ribosomes Adopt an Altered Geometry at the Peptidyl Transferase Center
por: Bhushan, Shashi, et al.
Publicado: (2011)