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Insulin BBB pharmacokinetics in young apoE male and female transgenic mice
In addition to age, apolipoprotein E4 (E4), female sex, or a combination of both synergistically increase the risk for the development of Alzheimer’s disease (AD). Why these risk factors predispose an individual to developing AD later in life is the target of the current investigation. Central nervo...
Autores principales: | Rhea, Elizabeth M., Torres, Eileen Ruth S., Raber, Jacob, Banks, William A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993976/ https://www.ncbi.nlm.nih.gov/pubmed/32004344 http://dx.doi.org/10.1371/journal.pone.0228455 |
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