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Immune responses to Mycobacterium tuberculosis membrane-associated antigens including alpha crystallin can potentially discriminate between latent infection and active tuberculosis disease
Changes in expression of membrane antigens may accompany the transition of Mycobacterium tuberculosis (Mtb) from ‘dormant’ to ‘active’ states. We have determined whether antibody and T cell responses to Mtb membrane (MtM)-associated antigens, especially the latency-induced protein alpha crystallin (...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994005/ https://www.ncbi.nlm.nih.gov/pubmed/32004357 http://dx.doi.org/10.1371/journal.pone.0228359 |