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Single-round isolation of diverse RNA aptamers from a random sequence pool

Aptamers are oligonucleotide ligands with specific binding affinity to target molecules. Generally, RNA aptamers are selected from an RNA pool with random sequences, using the technique termed SELEX, in which the target-binding RNA molecules are repeatedly isolated and exponentially amplified. Despi...

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Detalles Bibliográficos
Autores principales: Imashimizu, Masahiko, Takahashi, Masaki, Amano, Ryo, Nakamura, Yoshikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994090/
https://www.ncbi.nlm.nih.gov/pubmed/32161798
http://dx.doi.org/10.1093/biomethods/bpy004