Cargando…
CFTR dysregulation drives active selection of the gut microbiome
Patients with cystic fibrosis (CF) have altered fecal microbiomes compared to those of healthy controls. The magnitude of this dysbiosis correlates with measures of CF gastrointestinal (GI) disease, including GI inflammation and nutrient malabsorption. However, whether this dysbiosis is caused by mu...
Autores principales: | Meeker, Stacey M., Mears, Kevin S., Sangwan, Naseer, Brittnacher, Mitchell J., Weiss, Eli J., Treuting, Piper M., Tolley, Nicholas, Pope, Christopher E., Hager, Kyle R., Vo, Anh T., Paik, Jisun, Frevert, Charles W., Hayden, Hillary S., Hoffman, Lucas R., Miller, Samuel I., Hajjar, Adeline M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994172/ https://www.ncbi.nlm.nih.gov/pubmed/31961914 http://dx.doi.org/10.1371/journal.ppat.1008251 |
Ejemplares similares
-
Protective Effects of ALDH1A Enzyme Inhibition on Helicobacter-Induced Colitis in Smad3(−/−) Mice are Associated with Altered α4ß7 Integrin Expression on Activated T Cells
por: Seamons, Audrey, et al.
Publicado: (2020) -
Characterization of Dextran Sodium Sulfate-Induced Inflammation and Colonic Tumorigenesis in Smad3
(−/−) Mice with Dysregulated TGFβ
por: Seamons, Audrey, et al.
Publicado: (2013) -
Infants with cystic fibrosis have altered fecal functional capacities with potential clinical and metabolic consequences
por: Eng, Alexander, et al.
Publicado: (2021) -
Investigation of an ALDH1A1-specific inhibitor for suppression of weight gain in a diet induced mouse model of obesity
por: Haenisch, Michael, et al.
Publicado: (2021) -
Humanized TLR7/8 Expression Drives Proliferative Multisystemic Histiocytosis in C57BL/6 Mice
por: Snyder, Jessica M., et al.
Publicado: (2014)