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Primary hyperparathyroidism with extensive brown tumours and distal humerus fracture—A case report

INTRODUCTION: A brown tumour is benign bony lesion caused by localized, rapid osteoclastic turnover, resulting from hyperparathyroidism. In this report, we present a case of 25-year-old woman with multiple swelling and bone pain. Plain radiographs of the affected bones revealed multiple erosive bone...

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Detalles Bibliográficos
Autores principales: kumar Yadav, Amit, Pawar, Eknath, Harsoor, Abhishek, kumar G S, Prasanna, Rohra, Hitesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994264/
https://www.ncbi.nlm.nih.gov/pubmed/31991305
http://dx.doi.org/10.1016/j.ijscr.2019.12.042
Descripción
Sumario:INTRODUCTION: A brown tumour is benign bony lesion caused by localized, rapid osteoclastic turnover, resulting from hyperparathyroidism. In this report, we present a case of 25-year-old woman with multiple swelling and bone pain. Plain radiographs of the affected bones revealed multiple erosive bone tumours, which were diagnosed as brown tumours associated with primary hyperparathyroidism. CASE REPORT: A 25 year old female presented with swelling in left elbow since 1 month along with multiple swelling in body. Patient had pain in left elbow after trivial fall. X-ray showed lytic lesion of left elbow with pathological fracture. Biopsy was suggestive of brown tumour of distal humerus. DISCUSSION: We managed this case with reconstruction of defect with fibula grafting and plating. CONCLUSION: Pathological fracture in young adult should always be properly investigated. A high index of suspicion is necessary to diagnose unusual presentation of Primary Hyperparathyroidism.