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Estrogen receptor-α in female skeletal muscle is not required for regulation of muscle insulin sensitivity and mitochondrial regulation

OBJECTIVE: Estrogen receptor-α (ERα) is a nuclear receptor family member thought to substantially contribute to the metabolic regulation of skeletal muscle. However, previous mouse models utilized to assess the necessity of ERα signaling in skeletal muscle were confounded by altered developmental pr...

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Detalles Bibliográficos
Autores principales: Iñigo, Melissa R., Amorese, Adam J., Tarpey, Michael D., Balestrieri, Nicholas P., Jones, Keith G., Patteson, Daniel J., Jackson, Kathryn C., Torres, Maria.J., Lin, Chien-Te, Smith, Cody D., Heden, Timothy D., McMillin, Shawna L., Weyrauch, Luke A., Stanley, Erin C., Schmidt, Cameron A., Kilburg-Basnyat, Brita B., Reece, Sky W., Psaltis, Christine E., Leinwand, Leslie A., Funai, Katsu, McClung, Joseph M., Gowdy, Kymberly M., Witczak, Carol A., Lowe, Dawn A., Neufer, P. Darrell, Spangenburg, Espen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994285/
https://www.ncbi.nlm.nih.gov/pubmed/32180550
http://dx.doi.org/10.1016/j.molmet.2019.12.010