CRISPR-Cpf1 Activation of Endogenous BMP4 Gene for Osteogenic Differentiation of Umbilical-Cord-Derived Mesenchymal Stem Cells

The CRISPR systems provide powerful genome-editing tools for wide applications in biological and medical research fields. However, the safety issue due to off-target effects of CRISPR has been one of the major hindrances of its application to regenerative medicine. The conventional CRISPR system has...

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Detalles Bibliográficos
Autores principales: Choi, Jaehoon, Bae, Taegeun, Byambasuren, Ninj, Park, Seong-Ho, Jo, Chris H., Kim, Dokyoung, Hur, Junho K., Hwang, Nathaniel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994413/
https://www.ncbi.nlm.nih.gov/pubmed/32021879
http://dx.doi.org/10.1016/j.omtm.2019.12.010

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