A bispecific IgG format containing four independent antigen binding sites

Bispecific antibodies come in many different formats, including the particularly interesting two-in-one antibodies, where one conventional IgG binds two different antigens. The IgG format allows these antibodies to mediate Fc-related functionality, and their wild-type structure ensures low immunogen...

Descripción completa

Detalles Bibliográficos
Autores principales: Ljungars, Anne, Schiött, Torbjörn, Mattson, Ulrika, Steppa, Jessica, Hambe, Björn, Semmrich, Monika, Ohlin, Mats, Tornberg, Ulla-Carin, Mattsson, Mikael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994471/
https://www.ncbi.nlm.nih.gov/pubmed/32005942
http://dx.doi.org/10.1038/s41598-020-58150-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994471/
https://www.ncbi.nlm.nih.gov/pubmed/32005942
http://dx.doi.org/10.1038/s41598-020-58150-z

Ejemplares similares