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A bispecific IgG format containing four independent antigen binding sites
Bispecific antibodies come in many different formats, including the particularly interesting two-in-one antibodies, where one conventional IgG binds two different antigens. The IgG format allows these antibodies to mediate Fc-related functionality, and their wild-type structure ensures low immunogen...
Autores principales: | Ljungars, Anne, Schiött, Torbjörn, Mattson, Ulrika, Steppa, Jessica, Hambe, Björn, Semmrich, Monika, Ohlin, Mats, Tornberg, Ulla-Carin, Mattsson, Mikael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994471/ https://www.ncbi.nlm.nih.gov/pubmed/32005942 http://dx.doi.org/10.1038/s41598-020-58150-z |
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