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Synergistic effects of repair, resilience and retention of damage determine the conditions for replicative ageing

Accumulation of damaged proteins is a hallmark of ageing, occurring in organisms ranging from bacteria and yeast to mammalian cells. During cell division in Saccharomyces cerevisiae, damaged proteins are retained within the mother cell, resulting in an ageing mother while a new daughter cell exhibit...

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Detalles Bibliográficos
Autores principales: Borgqvist, Johannes, Welkenhuysen, Niek, Cvijovic, Marija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994596/
https://www.ncbi.nlm.nih.gov/pubmed/32005954
http://dx.doi.org/10.1038/s41598-020-58444-2