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Synergistic effects of repair, resilience and retention of damage determine the conditions for replicative ageing
Accumulation of damaged proteins is a hallmark of ageing, occurring in organisms ranging from bacteria and yeast to mammalian cells. During cell division in Saccharomyces cerevisiae, damaged proteins are retained within the mother cell, resulting in an ageing mother while a new daughter cell exhibit...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994596/ https://www.ncbi.nlm.nih.gov/pubmed/32005954 http://dx.doi.org/10.1038/s41598-020-58444-2 |