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Surface protein imputation from single cell transcriptomes by deep neural networks
While single cell RNA sequencing (scRNA-seq) is invaluable for studying cell populations, cell-surface proteins are often integral markers of cellular function and serve as primary targets for therapeutic intervention. Here we propose a transfer learning framework, single cell Transcriptome to Prote...
Autores principales: | Zhou, Zilu, Ye, Chengzhong, Wang, Jingshu, Zhang, Nancy R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994606/ https://www.ncbi.nlm.nih.gov/pubmed/32005835 http://dx.doi.org/10.1038/s41467-020-14391-0 |
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