Evidence for an ancient BRCA1 pathogenic variant in inherited breast cancer patients from Senegal

BRCA1 and BRCA2 are the most incriminated genes in inherited breast/ovarian cancers. Several pathogenic variants of these genes conferring genetic predisposition have been described in different populations but rarely in sub-Saharan Africa. The objectives of this study were to identify pathogenic va...

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Detalles Bibliográficos
Autores principales: Ndiaye, Rokhaya, Diop, Jean Pascal Demba, Bourdon-Huguenin, Violaine, Dem, Ahmadou, Diouf, Doudou, Dieng, Mamadou Moustapha, Diop, Pape Saloum, Kane Gueye, Serigne Modou, Ba, Seydi Abdoul, Dia, Yacouba, Ka, Sidy, Mbengue, Babacar, Thiam, Alassane, Sylla Niang, Maguette, Gueye, Papa Madieye, Faye, Oumar, Lopez Sall, Philomene, Cisse, Aynina, Diop, Papa Amadou, Sobol, Hagay, Dieye, Alioune
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994613/
https://www.ncbi.nlm.nih.gov/pubmed/32025337
http://dx.doi.org/10.1038/s41525-020-0114-7

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