A transcriptome-wide association study based on 27 tissues identifies 106 genes potentially relevant for disease pathology in age-related macular degeneration

Genome-wide association studies (GWAS) for late stage age-related macular degeneration (AMD) have identified 52 independent genetic variants with genome-wide significance at 34 genomic loci. Typically, such an approach rarely results in the identification of functional variants implicating a defined...

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Detalles Bibliográficos
Autores principales: Strunz, Tobias, Lauwen, Susette, Kiel, Christina, Hollander, Anneke den, Weber, Bernhard H. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994629/
https://www.ncbi.nlm.nih.gov/pubmed/32005911
http://dx.doi.org/10.1038/s41598-020-58510-9

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