Fibroblast mitochondria in idiopathic Parkinson’s disease display morphological changes and enhanced resistance to depolarization

Mitochondrial dysfunction is a hallmark in idiopathic Parkinson’s disease (IPD). Here, we established screenable phenotypes of mitochondrial morphology and function in primary fibroblasts derived from patients with IPD. Upper arm punch skin biopsy was performed in 41 patients with mid-stage IPD and...

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Detalles Bibliográficos
Autores principales: Antony, P. M. A., Kondratyeva, O., Mommaerts, K., Ostaszewski, M., Sokolowska, K., Baumuratov, A. S., Longhino, L., Poulain, J. F., Grossmann, D., Balling, R., Krüger, R., Diederich, N. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994699/
https://www.ncbi.nlm.nih.gov/pubmed/32005875
http://dx.doi.org/10.1038/s41598-020-58505-6

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