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Nox2 dependent redox-regulation of microglial response to amyloid-β stimulation and microgliosis in aging

Microglia express constitutively a Nox2 enzyme that is involved in neuroinflammation by the generation of reactive oxygen species (ROS). Amyloid β (Aβ) plays a crucial role in Alzheimer’s disease. However, the mechanism of Aβ-induced microglial dysfunction and redox-regulation of microgliosis in agi...

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Detalles Bibliográficos
Autores principales:	Geng, Li, Fan, Lampson M., Liu, Fangfei, Smith, Colin, Li, Jian -Mei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994719/ https://www.ncbi.nlm.nih.gov/pubmed/32005915 http://dx.doi.org/10.1038/s41598-020-58422-8

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