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A computational model for understanding the oligomerization mechanisms of TNF receptor superfamily

By recognizing members in the tumor necrosis factor (TNF) receptor superfamily, TNF ligand proteins function as extracellular cytokines to activate various signaling pathways involved in inflammation, proliferation, and apoptosis. Most ligands in TNF superfamily are trimeric and can simultaneously b...

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Detalles Bibliográficos
Autores principales: Su, Zhaoqian, Wu, Yinghao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994755/
https://www.ncbi.nlm.nih.gov/pubmed/32021664
http://dx.doi.org/10.1016/j.csbj.2019.12.016