Cargando…
Developing an animal model to detect drug–drug interactions impacting drug-induced respiratory depression()
Opioids and benzodiazepines were frequently co-prescribed to patients with pain and psychiatric or neurological disorders; however, co-prescription of these drugs increased the risk for severe respiratory depression and death. Consequently, the U.S. Food and Drug Administration added boxed label war...
Autores principales: | Xu, Lin, Chockalingam, Ashok, Stewart, Sharron, Shea, Katherine, Matta, Murali K., Narayanasamy, Suresh, Pilli, Nageswara R., Volpe, Donna A., Weaver, James, Zhu, Hao, Davis, Michael C., Rouse, Rodney |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994827/ https://www.ncbi.nlm.nih.gov/pubmed/32021808 http://dx.doi.org/10.1016/j.toxrep.2020.01.008 |
Ejemplares similares
-
Effects of sedative psychotropic drugs combined with oxycodone on respiratory depression in the rat
por: Xu, Lin, et al.
Publicado: (2021) -
A high-throughput bioanalytical assay to support pharmacokinetic interaction study of oxycodone and diazepam in Sprague Dawley rats
por: Pilli, Nageswara R., et al.
Publicado: (2020) -
Determination of Non-Transferrin Bound Iron, Transferrin Bound Iron, Drug Bound Iron and Total Iron in Serum in a Rats after IV Administration of Sodium Ferric Gluconate Complex by Simple Ultrafiltration Inductively Coupled Plasma Mass Spectrometric Detection
por: Matta, Murali K., et al.
Publicado: (2018) -
Evaluation of Immunocompetent Urinary Tract Infected Balb/C Mouse Model For the Study of Antibiotic Resistance Development Using Escherichia Coli CFT073 Infection
por: Chockalingam, Ashok, et al.
Publicado: (2019) -
Comparative Evaluation of U.S. Brand and Generic Intravenous Sodium Ferric Gluconate Complex in Sucrose Injection: Biodistribution after Intravenous Dosing in Rats
por: Beekman, Christopher R., et al.
Publicado: (2017)