Integrated lipidomic and transcriptomic analyses identify altered nerve triglycerides in mouse models of prediabetes and type 2 diabetes

Peripheral neuropathy (PN) is a complication of prediabetes and type 2 diabetes (T2D). Increasing evidence suggests that factors besides hyperglycaemia contribute to PN development, including dyslipidaemia. The objective of this study was to determine differential lipid classes and altered gene expr...

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Detalles Bibliográficos
Autores principales: O'Brien, Phillipe D., Guo, Kai, Eid, Stephanie A., Rumora, Amy E., Hinder, Lucy M., Hayes, John M., Mendelson, Faye E., Hur, Junguk, Feldman, Eva L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994925/
https://www.ncbi.nlm.nih.gov/pubmed/31822493
http://dx.doi.org/10.1242/dmm.042101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994925/
https://www.ncbi.nlm.nih.gov/pubmed/31822493
http://dx.doi.org/10.1242/dmm.042101

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