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HCT116 colorectal liver metastases exacerbate muscle wasting in a mouse model for the study of colorectal cancer cachexia

Colorectal cancer (CRC) is often accompanied by formation of liver metastases (LM) and skeletal muscle wasting, i.e. cachexia. Despite affecting the majority of CRC patients, cachexia remains underserved, understudied and uncured. Animal models for the study of CRC-induced cachexia, in particular mo...

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Detalles Bibliográficos
Autores principales: Huot, Joshua R., Novinger, Leah J., Pin, Fabrizio, Bonetto, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994937/
https://www.ncbi.nlm.nih.gov/pubmed/31915140
http://dx.doi.org/10.1242/dmm.043166