Modelling the pathogenesis of X-linked distal hereditary motor neuropathy using patient-derived iPSCs

ATP7A encodes a copper-transporting P-type ATPase and is one of 23 genes in which mutations produce distal hereditary motor neuropathy (dHMN), a group of diseases characterized by length-dependent axonal degeneration of motor neurons. We have generated induced pluripotent stem cell (iPSC)-derived mo...

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Detalles Bibliográficos
Autores principales: Perez-Siles, Gonzalo, Cutrupi, Anthony, Ellis, Melina, Kuriakose, Jakob, La Fontaine, Sharon, Mao, Di, Uesugi, Motonari, Takata, Reinaldo I., Speck-Martins, Carlos E., Nicholson, Garth, Kennerson, Marina L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994953/
https://www.ncbi.nlm.nih.gov/pubmed/31969342
http://dx.doi.org/10.1242/dmm.041541

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994953/
https://www.ncbi.nlm.nih.gov/pubmed/31969342
http://dx.doi.org/10.1242/dmm.041541

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