Oral administration of a synthetic vinyl-ether plasmalogen normalizes open field activity in a mouse model of rhizomelic chondrodysplasia punctata

Rhizomelic chondrodysplasia punctata (RCDP) is a rare genetic disorder caused by mutations in peroxisomal genes essential for plasmalogen biosynthesis. Plasmalogens are a class of membrane glycerophospholipids containing a vinyl-ether-linked fatty alcohol at the sn-1 position that affect functions i...

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Detalles Bibliográficos
Autores principales: Fallatah, Wedad, Smith, Tara, Cui, Wei, Jayasinghe, Dushmanthi, Di Pietro, Erminia, Ritchie, Shawn A., Braverman, Nancy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994958/
https://www.ncbi.nlm.nih.gov/pubmed/31862688
http://dx.doi.org/10.1242/dmm.042499

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994958/
https://www.ncbi.nlm.nih.gov/pubmed/31862688
http://dx.doi.org/10.1242/dmm.042499

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