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Does urethral length affect continence outcomes following robot assisted laparoscopic radical prostatectomy (RALP)?

BACKGROUND: Post-operative urinary incontinence is a significant concern for patients choosing to undergo a radical prostatectomy (RP) for treatment of prostate cancer. The aim of our study was to determine the effect of pre-operative MUL on 12 month continence outcomes in men having robot-assisted...

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Autores principales: Lin, Diwei, O’Callaghan, Michael, David, Rowan, Fuller, Andrew, Wells, Richard, Sutherland, Peter, Foreman, Darren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995073/
https://www.ncbi.nlm.nih.gov/pubmed/32005113
http://dx.doi.org/10.1186/s12894-020-0578-x
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author Lin, Diwei
O’Callaghan, Michael
David, Rowan
Fuller, Andrew
Wells, Richard
Sutherland, Peter
Foreman, Darren
author_facet Lin, Diwei
O’Callaghan, Michael
David, Rowan
Fuller, Andrew
Wells, Richard
Sutherland, Peter
Foreman, Darren
author_sort Lin, Diwei
collection PubMed
description BACKGROUND: Post-operative urinary incontinence is a significant concern for patients choosing to undergo a radical prostatectomy (RP) for treatment of prostate cancer. The aim of our study was to determine the effect of pre-operative MUL on 12 month continence outcomes in men having robot-assisted laparoscopic prostatectomy (RALP). METHODS: We use the South Australian Prostate Cancer Clinical Outcomes Collaborative (SA-PCCOC) database, to identify 602 patients who had undergone RALP by a high volume surgeon. Only patients who received an assessment and education by a specialist pelvic floor physiotherapist, had completed EPIC questionnaires before treatment and did not have radiotherapy treatment within 12 months of surgery were included. MUL measurements were taken from pre-operative magnetic resonance imaging (MRI) scans. The short-form version of the Expanded Prostate Cancer Index Composite (EPIC-26) was used to measure continence outcomes. Continence was defined as 100/100 in the EPIC-26 Urinary Continence domain score. RESULTS: The observed median MUL in this study was 14.6 mm. There was no association between MUL and baseline continence. MUL was associated with continence at 12 months post RALP (OR 1.13, 95% CI 1.03–1.21, p = 0.0098). In men who were continent before surgery, MUL was associated with return to continence at 12 months after RALP (OR 1.15, 1.05–1.28, p = 0.006). MUL was also associated with change in continence after surgery (β = 1.22, p = 0.002). CONCLUSIONS: MUL had no effect on baseline continence but had a positive and significant association with continence outcomes over 12 months post RALP.
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spelling pubmed-69950732020-02-04 Does urethral length affect continence outcomes following robot assisted laparoscopic radical prostatectomy (RALP)? Lin, Diwei O’Callaghan, Michael David, Rowan Fuller, Andrew Wells, Richard Sutherland, Peter Foreman, Darren BMC Urol Research Article BACKGROUND: Post-operative urinary incontinence is a significant concern for patients choosing to undergo a radical prostatectomy (RP) for treatment of prostate cancer. The aim of our study was to determine the effect of pre-operative MUL on 12 month continence outcomes in men having robot-assisted laparoscopic prostatectomy (RALP). METHODS: We use the South Australian Prostate Cancer Clinical Outcomes Collaborative (SA-PCCOC) database, to identify 602 patients who had undergone RALP by a high volume surgeon. Only patients who received an assessment and education by a specialist pelvic floor physiotherapist, had completed EPIC questionnaires before treatment and did not have radiotherapy treatment within 12 months of surgery were included. MUL measurements were taken from pre-operative magnetic resonance imaging (MRI) scans. The short-form version of the Expanded Prostate Cancer Index Composite (EPIC-26) was used to measure continence outcomes. Continence was defined as 100/100 in the EPIC-26 Urinary Continence domain score. RESULTS: The observed median MUL in this study was 14.6 mm. There was no association between MUL and baseline continence. MUL was associated with continence at 12 months post RALP (OR 1.13, 95% CI 1.03–1.21, p = 0.0098). In men who were continent before surgery, MUL was associated with return to continence at 12 months after RALP (OR 1.15, 1.05–1.28, p = 0.006). MUL was also associated with change in continence after surgery (β = 1.22, p = 0.002). CONCLUSIONS: MUL had no effect on baseline continence but had a positive and significant association with continence outcomes over 12 months post RALP. BioMed Central 2020-01-31 /pmc/articles/PMC6995073/ /pubmed/32005113 http://dx.doi.org/10.1186/s12894-020-0578-x Text en © The Author(s). 2020 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Lin, Diwei
O’Callaghan, Michael
David, Rowan
Fuller, Andrew
Wells, Richard
Sutherland, Peter
Foreman, Darren
Does urethral length affect continence outcomes following robot assisted laparoscopic radical prostatectomy (RALP)?
title Does urethral length affect continence outcomes following robot assisted laparoscopic radical prostatectomy (RALP)?
title_full Does urethral length affect continence outcomes following robot assisted laparoscopic radical prostatectomy (RALP)?
title_fullStr Does urethral length affect continence outcomes following robot assisted laparoscopic radical prostatectomy (RALP)?
title_full_unstemmed Does urethral length affect continence outcomes following robot assisted laparoscopic radical prostatectomy (RALP)?
title_short Does urethral length affect continence outcomes following robot assisted laparoscopic radical prostatectomy (RALP)?
title_sort does urethral length affect continence outcomes following robot assisted laparoscopic radical prostatectomy (ralp)?
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995073/
https://www.ncbi.nlm.nih.gov/pubmed/32005113
http://dx.doi.org/10.1186/s12894-020-0578-x
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