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BCREval: a computational method to estimate the bisulfite conversion ratio in WGBS

BACKGROUND: Whole genome bisulfite sequencing (WGBS) also known as BS-seq has been widely used to measure the methylation of whole genome at single-base resolution. One of the key steps in the assay is converting unmethylated cytosines into thymines (BS conversion). Incomplete conversion of unmethyl...

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Detalles Bibliográficos
Autores principales:	Zhou, Junhua, Zhao, Minqiong, Sun, Zefang, Wu, Feilong, Liu, Yucong, Liu, Xianghua, He, Zuping, He, Quanze, He, Quanyuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995172/ https://www.ncbi.nlm.nih.gov/pubmed/32005131 http://dx.doi.org/10.1186/s12859-019-3334-z

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