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Tetrandrine Suppresses Transient Receptor Potential Cation Channel Protein 6 Overexpression- Induced Podocyte Damage via Blockage of RhoA/ROCK1 Signaling

OBJECTIVE: Podocyte damage is common in many renal diseases characterized by proteinuria. Transient receptor potential cation channel protein 6 (TRPC6) plays an important role in renal function through its regulation of intracellular Ca(2+) influx and RhoA/ROCK pathways. Chinese herb Stephania tetra...

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Detalles Bibliográficos
Autores principales:	Yu, Jin, Zhu, Caifeng, Yin, Jiazhen, Yu, Dongrong, Wan, Feng, Tang, Xuanli, Jiang, Xue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995298/ https://www.ncbi.nlm.nih.gov/pubmed/32095070 http://dx.doi.org/10.2147/DDDT.S234262

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